Cryo-Electron Microscopy Scientist Job at Iowa State University, Ames, IA

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  • Iowa State University
  • Ames, IA

Job Description

Cryo-Electron Microscopy Scientist

The Office of Biotechnology at Iowa State University is seeking a Cryo-Electron Microscopy Scientist to join the team! This is a unique opportunity to direct a state-of-the-art core facility supporting high-impact research in structural biology, molecular biology, and interdisciplinary science. The Cryo-EM facility plays a central role in advancing Iowa State's research and education mission and contributes to strategic initiatives across campus and beyond. This position will be classified as a Research Scientist III.

In this role, you will be the primary scientific and technical lead overseeing the operation, maintenance, and user training associated with our Thermo Fisher Glacios microscope, Gatan K3 detector, and Thermo Fisher Vitrobot. The candidate will work independently to manage the instrumentation and is responsible for microscope alignment and sample loading. They will develop a workflow for the facility, including grid preparation, data collection, and analysis. The candidate will also be responsible for training users in grid preparation, data collection and analysis, including single-particle Cryo-EM software.

In this senior-level role, the candidate will contribute to Iowa State's thriving research environment by collaborating with faculty, mentoring students and visiting scientists, and offering expert consultation on project design and data interpretation for on-campus and off-campus clients. They will also have the opportunity to participate in grant proposals, co-author publications, and develop and lead workshops and training sessions in Cryo-EM.

Key responsibilities include:

  • Operate, maintain, and align Cryo-EM instrumentation; coordinate service visits and troubleshoot technical issues
  • Develop and optimize workflows for sample preparation, data collection, and single-particle analysis
  • Provide one-on-one training and group instruction for users on Cryo-EM techniques and software
  • Manage facility operations including budgeting, scheduling, billing, and rate structure development
  • Engage in collaborative research; contribute to grant proposals, publications, and report
  • Organize and teach Cryo-EM courses and workshops; mentor undergraduate and graduate researchers

The successful candidate for this role will be detail-oriented, self-motivated, and eager to advance structural biology research. They will have excellent organizational and project management skills along with strong communication and interpersonal skills to work effectively with a broad range of users and collaborators. This individual will also have a willingness to learn and adapt to evolving technologies.

This is a three year, fixed term position with the opportunity for renewal.

At Iowa State, you'll be part of a collegial and research-focused community. This position offers the chance to oversee direction of a premier facility, work at the forefront of structural biology, and shape the future of Cryo-EM training and research support on campus.

This posting will be open until filled. However, to receive full consideration, applications need to be submitted by July 27th, 2025.

Iowa State Employees enjoy comprehensive health and work-life benefits, including medical and dental; as well as:

  • Retirement benefits including defined benefit and defined contribution plans
  • Generous vacation, holiday and sick time and leave plans
  • Onsite childcare (Ames, Iowa)
  • Life insurance and long-term disability
  • Flexible Spending Accounts
  • Various voluntary benefits and discounts
  • Employee Assistance Program
  • Wellbeing program
Iowa State University

Job Tags

Fixed term contract, Work at office, Flexible hours,

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